Dr Renee Mosi
1998 - PhD Bio-organic Chemistry, University of British Columbia, Canada
1992 - BSc (1st Hons) Chemistry/Microbiology, University of Victoria, Canada
カナダ在住。改良された基質と抑制剤を用いた2つの糖転移酵素、グリコーゲンホスホリラーゼとシクロデクストリン糖転移酵素の反応のメカニズム等を博士研究。製薬研究に長年従事する経験豊富な熟練研究者。ガン治療のためのシステインプロテアーゼの抗菌剤と抑制剤として金属酵素の抑制剤の識別のための新しい分析評価を開発・実行。酵素学、レセプターに基づく細胞生物学、薬物代謝とタンパク質浄化と生産において専門知識持つ。また科学的な結果解明のためのシステムと手順をデザイン、標準化した。FDAガイドラインについての揺ぎ無い知識があり、GLPとGMP手順の訓練も受けている。Drug Information Association、International Society for the Study of Xenobiotics、Society for Biomolecular Screening、American Society of MicrobiologyおよびCanadian Society of Chemistryの専門会員。10の筆頭著者出版があり、生物学、生化学、化学と薬理学の分野で多数の校正を担当。エダンズ・グループでその幅広い経験と知識を活かす。
Dr Mosi’s PhD studies involved the mechanism of reaction of two alpha glycosyltransferases, glycogen phosphorylase and cyclodextrin glycosyltransferase, through the use of modified substrates and inhibitors. Dr Mosi is a senior research scientist with eight years’ experience in pharmaceutical drug research. She has developed and implemented novel assays for the purpose of the identification of inhibitors of metallo-enzymes as antibacterials and inhibitors of cysteine proteases for the treatment of cancer. Dr Mosi has applied expertise in enzymology, receptor based cell biology, drug metabolism and protein purification and production. As well, she has designed and standardized systems and procedures for interpreting scientific results. She also has a sound knowledge of FDA guidelines and is trained in GLP and GMP procedures. Dr Mosi is a past member of the Drug Information Association, International Society for the Study of Xenobiotics, Society for Biomolecular Screening, American Society of Microbiology, and the Canadian Society of Chemistry. As first author of 10 published, peer reviewed manuscripts, and as editor of numerous other papers in fields of biology, biochemistry, chemistry and pharmacology, Dr Mosi brings an extensive writing background to her editing work for Edanz Editing.


